Interactive Tour of the Archaeal Large Subunit


      Table of Contents

Introduction

Ribosomal RNA of the large subunit

Yarus analog bound to large subunit

Comparison of P-loop structures

An additional analog bound

No ribosomal proteins are near the site of peptide bond synthesis

Polypeptide Exit Tunnel

Environment of the critical nucleotide in the active site

Impact: The University of Massachusetts ribosome labs

References


Please be patient when you seen the "Movie playing" message.   It can include download time of large files over the internet at start of tour and in certain sections.   If the tour begins to behave poorly, it is best to go back to the page where the requirements are listed and enter the tour again.   You should close the old tour window.   The table of contents allows you to quickly return to where you left off.

Rotation is stopped as the default in this tour.    Using the mouse to click on and spin the molecule,  you can get the effect of rotating, while not bogging down your computer.   Rotation or spin can be turned on in the tool bar.  It takes a great deal of computing power to calculate the movements of all the elements associated with the large subunit.   Even with a good computer,  your response time in the right window may be slowed with spin on.  Let the movie finish and then try clicking.  Those familiar with Chime may choose to use Chime's Menu.   This can be difficult, particularly on a Mac when spin is on.  Commands sent via Chime's Menu will not be registered amongst the status alerts above the Chime image.

                                     

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Requirements and Preliminaries Page